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Sciatica+with lumbago

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M13_SCIATICA

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M54.3, M54.4
  • Hospital discharge: ICD-8 — 7170
  • Cause of death: ICD-10 — M54.3, M54.4
  • Cause of death: ICD-8 — 7170

2 out of 7 registries used, show all original rules.

21428

4. Check minimum number of events

None

21428

5. Include endpoints

None

21428

6. Filter based on genotype QC (FinnGen only)

20699

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 175823 100824 74031
Only index persons 168115 97570 70545
Unadjusted period prevalence (%)
Whole population 2.53 2.89 2.07
Only index persons 3.21 3.59 2.69
Median age at first event (years)
Whole population 51.44 52.58 50.01
Only index persons 51.14 52.24 49.62

-FinnGen-

Key figures

All Female Male
Number of individuals 20699 13119 7580
Unadjusted period prevalence (%) 5.14 5.70 4.17
Median age at first event (years) 52.83 51.86 54.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_SCIATICA – Sciatica+with lumbago

GWS hits: 6

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