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This is a non-core endpoint: only basic statistics are computed.

Kaschin-Beck disease

M13_KASHINBECK

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M12.1
  • Cause of death: ICD-10 M12.1

2 out of 7 registries used, show all original rules.

23

4. Check minimum number of events

None

23

5. Include endpoints

None

23

6. Filter based on genotype QC (FinnGen only)

22

Control definitions (FinnGen only)

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M12
Name in latin Morbus Kashin-Beck

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 287 187 100
Only index persons 269 177 92
Unadjusted period prevalence (%)
Whole population 0.00 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population - 63.85 58.81
Only index persons 61.33 62.76 58.59

-FinnGen-

Key figures

All Female Male
Number of individuals 22 14 8
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 60.76 57.45 66.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_KASHINBECK – Kaschin-Beck disease

GWS hits: -

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