Early lumbar disc prolapse, operated

M13_EARLY_LUMBAR_PROLAPSE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: 16<=EVENT_AGE<=44

Registry filters:

  • Hospital discharge: ICD-10 M51.1
  • Cause of death: ICD-10 M51.1
  • Operations: NOMESCO codes ^ABC16|^ABC07|^ABC26

3 out of 7 registries used, show all original rules.

9941

4. Check minimum number of events

None

9941

5. Include endpoints

None

9941

6. Filter based on genotype QC (FinnGen only)

9607

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 91713 40838 50386
Only index persons 90026 40442 49584
Unadjusted period prevalence (%)
Whole population 1.30 1.17 1.41
Only index persons 1.71 1.49 1.89
Median age at first event (years)
Whole population 35.38 35.54 35.25
Only index persons 35.35 35.52 35.22

-FinnGen-

Key figures

All Female Male
Number of individuals 9607 5699 3908
Unadjusted period prevalence (%) 2.34 2.47 2.15
Median age at first event (years) 36.50 36.15 37.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_EARLY_LUMBAR_PROLAPSE – Early lumbar disc prolapse, operated

GWS hits: 10

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