Other and unspecified urticaria

L12_URTICA_NAS

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L50.8, L50.9
  • Hospital discharge: ICD-9 708[8-9]
  • Hospital discharge: ICD-8 708
  • Cause of death: ICD-10 L50.8, L50.9
  • Cause of death: ICD-9 708[8-9]
  • Cause of death: ICD-8 708

2 out of 7 registries used, show all original rules.

7282

4. Check minimum number of events

None

7282

5. Include endpoints

None

7282

6. Filter based on genotype QC (FinnGen only)

6986

Control definitions (FinnGen only)

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 77117 45690 31011
Only index persons 66004 40315 25689
Unadjusted period prevalence (%)
Whole population 1.13 1.31 0.87
Only index persons 1.29 1.48 0.98
Median age at first event (years)
Whole population 28.20 33.41 20.39
Only index persons 30.53 35.04 23.44

-FinnGen-

Key figures

All Female Male
Number of individuals 6986 4983 2003
Unadjusted period prevalence (%) 1.86 2.16 1.10
Median age at first event (years) 40.12 39.76 41.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: L12_URTICA_NAS – Other and unspecified urticaria

GWS hits: 3

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