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Lupus erythematosus

DOID EFO Endpoint Browser PheWeb

L12_LUPUS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L93#
  • Hospital discharge: ICD-9 — 6954
  • Hospital discharge: ICD-8 — 6954|68611
  • Cause of death: ICD-10 — L93#
  • Cause of death: ICD-9 — 6954
  • Cause of death: ICD-8 — 6954|68611

2 out of 7 registries used, show all original rules.

736

4. Check minimum number of events

None

736

5. Include endpoints

None

736

6. Filter based on genotype QC (FinnGen only)

705

Control definitions (FinnGen only)

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Lupus erythematosus

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5703 4197 1469
Only index persons 5048 3789 1259
Unadjusted period prevalence (%)
Whole population 0.10 0.12 0.04
Only index persons 0.12 0.14 0.05
Median age at first event (years)
Whole population 54.73 55.76 51.68
Only index persons 53.96 55.11 50.50

-FinnGen-

Key figures

All Female Male
Number of individuals 705 535 170
Unadjusted period prevalence (%) 0.20 0.23 0.09
Median age at first event (years) 54.68 54.04 56.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_LUPUS – Lupus erythematosus

GWS hits: 1

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