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Erythema nodosum

DOID EFO Endpoint Browser PheWeb

L12_ERYTHEMANODOSUM

erythema infectiosum: usually a benign childhood condition characterized by a classic slapped-cheek appearance (see the image below) and lacy exanthem.It results from infection with human parvovirus (PV) B19, an erythrovirus.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L52
  • Hospital discharge: ICD-9 — 6952
  • Hospital discharge: ICD-8 — 69520
  • Cause of death: ICD-10 — L52
  • Cause of death: ICD-9 — 6952
  • Cause of death: ICD-8 — 69520

2 out of 7 registries used, show all original rules.

934

4. Check minimum number of events

None

934

5. Include endpoints

None

934

6. Filter based on genotype QC (FinnGen only)

904

Control definitions (FinnGen only)

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L50-L54
Name in latin Erythema nodosum

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9004 6843 2116
Only index persons 7799 5941 1858
Unadjusted period prevalence (%)
Whole population 0.16 0.20 0.06
Only index persons 0.18 0.22 0.07
Median age at first event (years)
Whole population 40.55 41.91 36.01
Only index persons 37.81 38.86 34.46

-FinnGen-

Key figures

All Female Male
Number of individuals 904 716 188
Unadjusted period prevalence (%) 0.27 0.31 0.10
Median age at first event (years) 38.88 38.39 40.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_ERYTHEMANODOSUM – Erythema nodosum

GWS hits: 2

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