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Chronic ulcer of skin, not elsewhere classified

DOID EFO Endpoint Browser PheWeb

L12_CHRONICULCEROFSKIN

chronic ulcer of skin: ['Chronic skin ulceration is a common complication of diabetes, peripheral vascular disease, and disorders that decrease mobility. Local ulcer care will be successful only if the underlying cause is correctly identified and steps are taken to reverse it.']

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L98.4
  • Hospital discharge: ICD-9 — 707[8-9]
  • Hospital discharge: ICD-8 — 707
  • Hospital discharge: excluded ICD-8 — 70700
  • Cause of death: ICD-10 — L98.4
  • Cause of death: ICD-9 — 707[8-9]
  • Cause of death: ICD-8 — 707
  • Cause of death: excluded ICD-8 — 70700

2 out of 7 registries used, show all original rules.

2052

4. Check minimum number of events

None

2052

5. Include endpoints

None

2052

6. Filter based on genotype QC (FinnGen only)

2001

Control definitions (FinnGen only)

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L98
Name in latin Ulcus chronicum cutis non alibi classificatum

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24012 13020 10742
Only index persons 18158 9740 8418
Unadjusted period prevalence (%)
Whole population 0.34 0.37 0.30
Only index persons 0.34 0.36 0.32
Median age at first event (years)
Whole population 68.83 72.35 64.68
Only index persons 68.70 72.24 64.60

-FinnGen-

Key figures

All Female Male
Number of individuals 2001 917 1084
Unadjusted period prevalence (%) 0.51 0.40 0.60
Median age at first event (years) 64.55 63.59 65.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_CHRONICULCEROFSKIN – Chronic ulcer of skin, not elsewhere classified

GWS hits: 1

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