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Acquired keratosis [keratoderma] palmaris et plantaris

DOID EFO Endpoint Browser PheWeb

L12_ACQKERAT

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L85.1
  • Hospital discharge: ICD-9 — 7011A|7011E|7011D
  • Hospital discharge: ICD-8 — 70110
  • Cause of death: ICD-10 — L85.1
  • Cause of death: ICD-9 — 7011A|7011E|7011D
  • Cause of death: ICD-8 — 70110

2 out of 7 registries used, show all original rules.

133

4. Check minimum number of events

None

133

5. Include endpoints

None

133

6. Filter based on genotype QC (FinnGen only)

128

Control definitions (FinnGen only)

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L85
Name in latin Keratosis (keratoderma) palmaris et plantaris acquisita

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1124 601 516
Only index persons 982 536 446
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 54.60 57.17 51.70
Only index persons 54.36 56.87 51.33

-FinnGen-

Key figures

All Female Male
Number of individuals 128 69 59
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 54.98 56.98 52.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_ACQKERAT – Acquired keratosis [keratoderma] palmaris et plantaris

GWS hits: -

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