Acne

L12_ACNE

acne: An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L70 Cause of death: ICD-10 — L70 2 out of 7 registries used, show all original rules.	3153
4. Check minimum number of events None	3153
5. Include endpoints L12_ACNE_VULGARIS L12_ACNE_CONGLOBLATA L12_ACNE_VARIOLIFORMIS L12_ACNE_TROPICA L12_ACNE_INFANT L12_ACNE_EXCOR L12_ACNE_NAS	3402
6. Filter based on genotype QC (FinnGen only)	3245

Control definitions (FinnGen only)

Control exclude L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L60-L75

Name in latin Acne

NAME	L12_ACNE
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_ACNE_VULGARIS\|L12_ACNE_CONGLOBLATA\|L12_ACNE_VARIOLIFORMIS\|L12_ACNE_TROPICA\|L12_ACNE_INFANT\|L12_ACNE_EXCOR\|L12_ACNE_NAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L70
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L70
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Acne based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	52364	25973	26178
Only index persons	51216	25574	25642
Unadjusted period prevalence (%)
Whole population	0.74	0.74	0.73
Only index persons	0.96	0.94	0.98
Median age at first event (years)
Whole population	20.29	21.46	19.05
Only index persons	20.23	21.46	19.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	3245	2068	1177
Unadjusted period prevalence (%)	0.81	0.90	0.65
Median age at first event (years)	24.33	26.51	20.50

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Acne

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Acne (L12_ACNE)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints