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Perforation of oesophagus

DOID EFO Endpoint Browser PheWeb

K11_PERFOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K22.3
  • Hospital discharge: ICD-9 — 5304
  • Hospital discharge: ICD-8 — 5304
  • Cause of death: ICD-10 — K22.3
  • Cause of death: ICD-9 — 5304
  • Cause of death: ICD-8 — 5304

2 out of 7 registries used, show all original rules.

130

4. Check minimum number of events

None

130

5. Include endpoints

None

130

6. Filter based on genotype QC (FinnGen only)

123

Control definitions (FinnGen only)

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K22
Name in latin Perforatio oesophagi

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1531 568 942
Only index persons 1177 448 729
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.02 0.02 0.03
Median age at first event (years)
Whole population 65.20 69.78 62.30
Only index persons 64.77 68.22 62.65

-FinnGen-

Key figures

All Female Male
Number of individuals 123 45 78
Unadjusted period prevalence (%) 0.03 0.02 0.04
Median age at first event (years) 63.03 61.05 64.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: K11_PERFOES – Perforation of oesophagus

GWS hits: -

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