Other diseases of pancreas

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K86.2, K86.3, K86.8, K86.9
  • Hospital discharge: ICD-9 577[2-9]
  • Hospital discharge: ICD-8 5779
  • Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9
  • Cause of death: ICD-9 577[2-9]
  • Cause of death: ICD-8 5779

2 out of 7 registries used, show all original rules.

2072

4. Check minimum number of events

None

2072

5. Include endpoints

None

2072

6. Filter based on genotype QC (FinnGen only)

2019

Control definitions (FinnGen only)

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19140 7325 11621
Only index persons 15380 6381 8999
Unadjusted period prevalence (%)
Whole population 0.28 0.21 0.32
Only index persons 0.30 0.23 0.34
Median age at first event (years)
Whole population 57.67 63.33 54.11
Only index persons 58.65 63.39 55.29

-FinnGen-

Key figures

All Female Male
Number of individuals 2019 871 1148
Unadjusted period prevalence (%) 0.52 0.38 0.63
Median age at first event (years) 61.80 63.05 60.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_PANCOTH – Other diseases of pancreas

GWS hits: 2

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