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Other diseases of oesophagus

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K11_OTHDISOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
  • Hospital discharge: ICD-9 — 530[5-9]
  • Hospital discharge: ICD-8 — 5302|5309
  • Hospital discharge: excluded ICD-10 — K22.7
  • Cause of death: ICD-10 — K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
  • Cause of death: ICD-9 — 530[5-9]
  • Cause of death: ICD-8 — 5302|5309

2 out of 7 registries used, show all original rules.

3266

4. Check minimum number of events

None

3266

5. Include endpoints

None

3266

6. Filter based on genotype QC (FinnGen only)

3175

Control definitions (FinnGen only)

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36883 15648 20710
Only index persons 26347 11658 14689
Unadjusted period prevalence (%)
Whole population 0.52 0.45 0.58
Only index persons 0.50 0.43 0.56
Median age at first event (years)
Whole population 58.42 61.45 56.04
Only index persons 55.31 57.65 53.45

-FinnGen-

Key figures

All Female Male
Number of individuals 3175 1388 1787
Unadjusted period prevalence (%) 0.82 0.60 0.98
Median age at first event (years) 56.02 54.66 57.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: K11_OTHDISOES – Other diseases of oesophagus

GWS hits: 1

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