Open bite

K11_OPEN_BITE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.24
  • Hospital discharge: ICD-10 K07.24
  • Cause of death: ICD-10 K07.24

3 out of 7 registries used, show all original rules.

1520

4. Check minimum number of events

None

1520

5. Include endpoints

None

1520

6. Filter based on genotype QC (FinnGen only)

1449

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 33503 19782 13652
Only index persons 28156 16874 11282
Unadjusted period prevalence (%)
Whole population 0.49 0.57 0.38
Only index persons 0.54 0.62 0.43
Median age at first event (years)
Whole population 12.86 13.55 11.78
Only index persons 14.52 15.12 13.62

-FinnGen-

Key figures

All Female Male
Number of individuals 1449 1092 357
Unadjusted period prevalence (%) 0.41 0.47 0.20
Median age at first event (years) 30.55 30.63 30.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_OPEN_BITE – Open bite

GWS hits: -

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