Mandibular prognathia

K11_MN_PROGN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.11
  • Hospital discharge: ICD-10 K07.11
  • Cause of death: ICD-10 K07.11

3 out of 7 registries used, show all original rules.

431

4. Check minimum number of events

None

431

5. Include endpoints

None

431

6. Filter based on genotype QC (FinnGen only)

397

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10540 4767 5746
Only index persons 9023 4093 4930
Unadjusted period prevalence (%)
Whole population 0.15 0.14 0.16
Only index persons 0.17 0.15 0.19
Median age at first event (years)
Whole population 13.23 13.24 13.15
Only index persons 14.49 14.49 14.49

-FinnGen-

Key figures

All Female Male
Number of individuals 397 235 162
Unadjusted period prevalence (%) 0.10 0.10 0.09
Median age at first event (years) 33.41 32.37 34.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_MN_PROGN – Mandibular prognathia

GWS hits: 1

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