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Functional dyspepsia

DOID EFO Endpoint Browser PheWeb

K11_FUNCDYSP

dyspepsia: An uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach pain, bloating, heartburn, nausea, and vomiting. Causes include gastritis, gastric ulcer, gastroesophageal reflux disease, pancreatic disease, and gallbladder disease.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K30
  • Hospital discharge: ICD-9 — 5368A
  • Hospital discharge: ICD-8 — 5361
  • Cause of death: ICD-10 — K30
  • Cause of death: ICD-9 — 5368A
  • Cause of death: ICD-8 — 5361

2 out of 7 registries used, show all original rules.

10084

4. Check minimum number of events

None

10084

5. Include endpoints

None

10084

6. Filter based on genotype QC (FinnGen only)

9680

Control definitions (FinnGen only)

Control exclude K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K20-K31
Name in latin Dyspepsia

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 84572 54528 29380
Only index persons 78993 51766 27227
Unadjusted period prevalence (%)
Whole population 1.30 1.56 0.82
Only index persons 1.61 1.90 1.04
Median age at first event (years)
Whole population 54.73 55.13 54.27
Only index persons 54.00 54.31 53.40

-FinnGen-

Key figures

All Female Male
Number of individuals 9680 6615 3065
Unadjusted period prevalence (%) 2.50 2.87 1.69
Median age at first event (years) 55.10 53.21 59.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: K11_FUNCDYSP – Functional dyspepsia

GWS hits: 2

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