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Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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J10_VOCALLARYNX

laryngeal disease: A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma. [database_cross_reference: NCIT:P378]

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J34, J38, J39
  • Hospital discharge: ICD-9 — 478
  • Hospital discharge: ICD-8 — 508
  • Hospital discharge: excluded ICD-8 — 50803
  • Cause of death: ICD-10 — J34, J38, J39
  • Cause of death: ICD-9 — 478
  • Cause of death: ICD-8 — 508
  • Cause of death: excluded ICD-8 — 50803

2 out of 7 registries used, show all original rules.

22379

4. Check minimum number of events

None

22379

5. Include endpoints

None

22379

6. Filter based on genotype QC (FinnGen only)

21556

Control definitions (FinnGen only)

Control exclude J10_UPPERDIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 183260 79082 103086
Only index persons 171084 74969 96115
Unadjusted period prevalence (%)
Whole population 2.60 2.27 2.88
Only index persons 3.27 2.76 3.67
Median age at first event (years)
Whole population 44.55 45.84 43.58
Only index persons 44.03 45.38 42.98

-FinnGen-

Key figures

All Female Male
Number of individuals 21556 10843 10713
Unadjusted period prevalence (%) 5.30 4.71 5.89
Median age at first event (years) 48.33 46.73 49.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: J10_VOCALLARYNX – Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

GWS hits: 1

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