respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
16149 |
4. Check minimum number of eventsNone |
16149 |
5. Include endpoints |
17270 |
6. Filter based on genotype QC (FinnGen only) |
16728 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Other diseases of pleura
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 165367 | 60443 | 102616 |
| Only index persons | 126825 | 47803 | 79022 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.45 | 1.73 | 2.87 |
| Only index persons | 2.54 | 1.76 | 3.02 |
| Median age at first event (years) | |||
| Whole population | 67.95 | 69.97 | 66.73 |
| Only index persons | 67.32 | 69.49 | 66.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 16728 | 5248 | 11480 |
| Unadjusted period prevalence (%) | 5.05 | 2.28 | 6.31 |
| Median age at first event (years) | 67.18 | 64.31 | 68.50 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: J10_PLEURA – Other diseases of pleura
GWS hits: 3
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