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Emphysema

DOID EFO Endpoint Browser PheWeb

J10_EMPHYSEMA

pleural empyema: The presence of pus in the thoracic cavity, between the visceral and parietal pleura. [database_cross_reference: NCIT:P378]

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J43
  • Hospital discharge: ICD-9 — 492
  • Hospital discharge: ICD-8 — 492
  • Cause of death: ICD-10 — J43
  • Cause of death: ICD-9 — 492
  • Cause of death: ICD-8 — 492

2 out of 7 registries used, show all original rules.

2188

4. Check minimum number of events

None

2188

5. Include endpoints

None

2188

6. Filter based on genotype QC (FinnGen only)

2128

Control definitions (FinnGen only)

Control exclude J10_LOWCHRON

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J40-J47
Name in latin Emphysema pulmonale

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 25262 6005 18635
Only index persons 14435 4338 10097
Unadjusted period prevalence (%)
Whole population 0.44 0.17 0.52
Only index persons 0.32 0.16 0.39
Median age at first event (years)
Whole population 68.18 67.77 68.36
Only index persons 67.82 66.92 68.21

-FinnGen-

Key figures

All Female Male
Number of individuals 2128 521 1607
Unadjusted period prevalence (%) 0.72 0.23 0.88
Median age at first event (years) 69.02 65.00 70.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: J10_EMPHYSEMA – Emphysema

GWS hits: 3

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