Unspecified acute lower respiratory infection

J10_ACUTELOWERNAS

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J22
  • Hospital discharge: ICD-8 46699
  • Cause of death: ICD-10 J22
  • Cause of death: ICD-8 46699

2 out of 7 registries used, show all original rules.

5284

4. Check minimum number of events

None

5284

5. Include endpoints

None

5284

6. Filter based on genotype QC (FinnGen only)

5109

Control definitions (FinnGen only)

Control exclude J10_LOWERINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J20-J22
Name in latin Infectio respiratoria inferior acuta non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 70784 28053 42315
Only index persons 58725 22829 35896
Unadjusted period prevalence (%)
Whole population 1.03 0.80 1.18
Only index persons 1.16 0.84 1.37
Median age at first event (years)
Whole population 33.27 52.55 20.18
Only index persons 29.85 45.27 20.03

-FinnGen-

Key figures

All Female Male
Number of individuals 5109 2049 3060
Unadjusted period prevalence (%) 1.36 0.89 1.68
Median age at first event (years) 30.46 44.21 21.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: J10_ACUTELOWERNAS – Unspecified acute lower respiratory infection

GWS hits: 3

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