All influenza (not pneumonia)

INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J10, J11
  • Hospital discharge: ICD-9 487
  • Hospital discharge: ICD-8 47[0-4]
  • Hospital discharge: excluded ICD-10 J10.0, J11.0
  • Hospital discharge: excluded ICD-9 4870
  • Hospital discharge: excluded ICD-8 471
  • Cause of death: ICD-10 J10, J11
  • Cause of death: ICD-9 487
  • Cause of death: ICD-8 47[0-4]
  • Cause of death: excluded ICD-10 4870
  • Cause of death: excluded ICD-9 471

2 out of 7 registries used, show all original rules.

5771

4. Check minimum number of events

None

5771

5. Include endpoints

None

5771

6. Filter based on genotype QC (FinnGen only)

5544

Control definitions (FinnGen only)

Control exclude J10_INFLUPNEU

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 86242 35278 50464
Only index persons 71348 28413 42935
Unadjusted period prevalence (%)
Whole population 1.24 1.01 1.41
Only index persons 1.40 1.04 1.64
Median age at first event (years)
Whole population 31.37 46.65 20.44
Only index persons 29.72 43.82 20.39

-FinnGen-

Key figures

All Female Male
Number of individuals 5544 2346 3198
Unadjusted period prevalence (%) 1.45 1.02 1.76
Median age at first event (years) 36.56 49.37 27.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: INFLUENZA – All influenza (not pneumonia)

GWS hits: 1

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