Sequelae of cerebrovascular disease

I9_SEQULAE

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I69
  • Hospital discharge: ICD-9 438
  • Cause of death: ICD-10 I69
  • Cause of death: ICD-9 438

2 out of 7 registries used, show all original rules.

13031

4. Check minimum number of events

None

13031

5. Include endpoints

None

13031

6. Filter based on genotype QC (FinnGen only)

12602

Control definitions (FinnGen only)

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I60-I69
Name in latin Sequelae morbi cerebrovascularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 187076 86341 97840
Only index persons 129587 61348 68239
Unadjusted period prevalence (%)
Whole population 2.62 2.47 2.73
Only index persons 2.44 2.26 2.60
Median age at first event (years)
Whole population 75.31 78.32 72.68
Only index persons 74.63 77.90 71.69

-FinnGen-

Key figures

All Female Male
Number of individuals 12602 4711 7891
Unadjusted period prevalence (%) 3.48 2.05 4.34
Median age at first event (years) 70.56 68.69 71.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_SEQULAE – Sequelae of cerebrovascular disease

GWS hits: 3

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