restrictive cardiomyopathy: A type of heart disorder referring to the inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and looses its flexibility. Causes include replacement of the myocardium with scar tissue, abnormal cellular infiltration of the myocardium, or deposition of a substance (e.g., amyloid) in the myocardium.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
101 |
4. Check minimum number of eventsNone |
101 |
5. Include endpointsNone |
101 |
6. Filter based on genotype QC (FinnGen only) |
99 |
Control definitions (FinnGen only)
Control exclude
I9_CARDMYO
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I42
Name in latin
Cardiomyopathia restrictiva
Similar endpoints
↥List of similar endpoints to
Restrictive cardiomyopathy
based on the number of shared cases.
Broader endpoints:
- Cardiomyopathies, Primary/intrinsic
- Cardiomyopathy (excluding other)
- Cardiomyopathy
- Other heart diseases
- Other heart diseases
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 790 | 397 | 379 |
| Only index persons | 553 | 298 | 255 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 68.55 | 72.32 | 64.68 |
| Only index persons | 70.21 | 73.52 | 66.34 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 99 | 41 | 58 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 66.03 | 69.19 | 63.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_CARDMYORESTR – Restrictive cardiomyopathy
GWS hits: -
Loading Relationships table