Other/unspecified disorders of vestibular function

H8_VESTIFUNCNAS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H81.8, H81.9
  • Hospital discharge: ICD-9 386[8-9]
  • Cause of death: ICD-10 H81.8, H81.9
  • Cause of death: ICD-9 386[8-9]

2 out of 7 registries used, show all original rules.

1041

4. Check minimum number of events

None

1041

5. Include endpoints

None

1041

6. Filter based on genotype QC (FinnGen only)

986

Control definitions (FinnGen only)

Control exclude H8_INNER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10780 6802 3882
Only index persons 9261 5920 3341
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.11
Only index persons 0.19 0.22 0.13
Median age at first event (years)
Whole population 64.51 66.08 61.73
Only index persons 62.36 63.66 60.06

-FinnGen-

Key figures

All Female Male
Number of individuals 986 599 387
Unadjusted period prevalence (%) 0.24 0.26 0.21
Median age at first event (years) 60.50 59.82 61.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function

GWS hits: -

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