Presbycusis

H8_HL_PRESBY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H91.1
  • Hospital discharge: ICD-9 3880
  • Hospital discharge: excluded ICD-9 2880X
  • Cause of death: ICD-10 H91.1
  • Cause of death: ICD-9 3880
  • Cause of death: excluded ICD-9 2880X

2 out of 7 registries used, show all original rules.

4698

4. Check minimum number of events

None

4698

5. Include endpoints

None

4698

6. Filter based on genotype QC (FinnGen only)

4538

Control definitions (FinnGen only)

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Presbyacusis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 64425 38004 26033
Only index persons 55412 33250 22162
Unadjusted period prevalence (%)
Whole population 0.94 1.09 0.73
Only index persons 1.07 1.22 0.85
Median age at first event (years)
Whole population 80.01 81.05 78.51
Only index persons 79.56 80.63 77.95

-FinnGen-

Key figures

All Female Male
Number of individuals 4538 2014 2524
Unadjusted period prevalence (%) 1.16 0.87 1.39
Median age at first event (years) 76.61 76.53 76.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H8_HL_PRESBY – Presbycusis

GWS hits: 2

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