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Other specified/unspecified hearing loss

DOID EFO Endpoint Browser PheWeb

H8_HL_NAS

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H91.8, H91.9
  • Hospital discharge: ICD-9 — 389[8-9]
  • Hospital discharge: ICD-8 — 389
  • Cause of death: ICD-10 — H91.8, H91.9
  • Cause of death: ICD-9 — 389[8-9]
  • Cause of death: ICD-8 — 389

2 out of 7 registries used, show all original rules.

2428

4. Check minimum number of events

None

2428

5. Include endpoints

None

2428

6. Filter based on genotype QC (FinnGen only)

2331

Control definitions (FinnGen only)

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30941 15915 14885
Only index persons 27863 14799 13064
Unadjusted period prevalence (%)
Whole population 0.44 0.46 0.42
Only index persons 0.52 0.54 0.50
Median age at first event (years)
Whole population 68.04 69.82 66.22
Only index persons 68.95 70.43 67.26

-FinnGen-

Key figures

All Female Male
Number of individuals 2331 1102 1229
Unadjusted period prevalence (%) 0.58 0.48 0.68
Median age at first event (years) 64.96 60.09 69.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H8_HL_NAS – Other specified/unspecified hearing loss

GWS hits: -

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