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Sudden idiopathic hearing loss

DOID EFO Endpoint Browser PheWeb

H8_HL_IDIOP

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H91.2
  • Hospital discharge: ICD-9 — 3882
  • Cause of death: ICD-10 — H91.2
  • Cause of death: ICD-9 — 3882

2 out of 7 registries used, show all original rules.

3235

4. Check minimum number of events

None

3235

5. Include endpoints

None

3235

6. Filter based on genotype QC (FinnGen only)

3128

Control definitions (FinnGen only)

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Hypacusis acuta idiopathica

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24447 12128 12214
Only index persons 23111 11603 11508
Unadjusted period prevalence (%)
Whole population 0.34 0.35 0.34
Only index persons 0.43 0.43 0.44
Median age at first event (years)
Whole population 58.15 58.52 57.78
Only index persons 57.56 57.96 57.15

-FinnGen-

Key figures

All Female Male
Number of individuals 3128 1616 1512
Unadjusted period prevalence (%) 0.76 0.70 0.83
Median age at first event (years) 58.27 56.23 60.44

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss

GWS hits: 2

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