Cholesteatoma of external ear

H8_EXT_CHOL

cholesteatoma of external ear: A cholesteatoma which involves invasion of the squamous tissue into a localized area of bony erosion of the ear canal. It may develop spontaneously or as a consequence of infection, trauma or surgery.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H60.4
  • Cause of death: ICD-10 H60.4

2 out of 7 registries used, show all original rules.

192

4. Check minimum number of events

None

192

5. Include endpoints

None

192

6. Filter based on genotype QC (FinnGen only)

183

Control definitions (FinnGen only)

Control exclude H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H60
Name in latin Cholesteatoma meatus acustici externi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2037 1011 1016
Only index persons 1930 964 966
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 64.36 65.08 63.74
Only index persons 63.84 64.05 63.64

-FinnGen-

Key figures

All Female Male
Number of individuals 183 74 109
Unadjusted period prevalence (%) 0.05 0.03 0.06
Median age at first event (years) 64.84 63.38 65.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H8_EXT_CHOL – Cholesteatoma of external ear

GWS hits: 1

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