Gestational diabetes (for exclusion)

GEST_DIABETES

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O24.4
  • Hospital discharge: ICD-9 6488A
  • Cause of death: ICD-10 O24.4
  • Cause of death: ICD-9 6488A

2 out of 7 registries used, show all original rules.

15525

4. Check minimum number of events

None

15525

5. Include endpoints

None

15525

6. Filter based on genotype QC (FinnGen only)

14718

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4
Parent code in ICD-10 O24
Name in latin Diabetes mellitus in gravidate apparens

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 124013 124013 -
Only index persons 122991 122991 -
Unadjusted period prevalence (%)
Whole population 3.55 3.55 -
Only index persons 4.52 4.52 -
Median age at first event (years)
Whole population - 31.54 -
Only index persons - 31.53 -

-FinnGen-

Key figures

All Female Male
Number of individuals 14718 14718 -
Unadjusted period prevalence (%) 6.39 6.39 -
Median age at first event (years) 31.74 31.74 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: GEST_DIABETES – Gestational diabetes (for exclusion)

GWS hits: 17

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