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Trigeminal neuralgia

DOID EFO Endpoint Browser PheWeb

G6_TRINEU

trigeminal neuralgia: Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain lasts a few seconds to a few minutes, and usually on only one side of the face. It can also cause muscle spasms in the face the same time as the pain. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of theface), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor or cyst. In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G50.0
  • Hospital discharge: ICD-9 — 3501
  • Hospital discharge: ICD-8 — 35199
  • Cause of death: ICD-10 — G50.0
  • Cause of death: ICD-9 — 3501
  • Cause of death: ICD-8 — 35199
  • KELA reimbursements: KELA codes — 119

3 out of 7 registries used, show all original rules.

1853

4. Check minimum number of events

None

1853

5. Include endpoints

None

1853

6. Filter based on genotype QC (FinnGen only)

1777

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G50
Name in latin Neuralgia trigeminalis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15546 10605 4805
Only index persons 13493 9534 3959
Unadjusted period prevalence (%)
Whole population 0.25 0.30 0.13
Only index persons 0.29 0.35 0.15
Median age at first event (years)
Whole population 56.64 56.10 57.82
Only index persons 54.85 54.41 55.90

-FinnGen-

Key figures

All Female Male
Number of individuals 1777 1241 536
Unadjusted period prevalence (%) 0.47 0.54 0.29
Median age at first event (years) 54.39 52.51 58.75

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_TRINEU – Trigeminal neuralgia

GWS hits: 1

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