Sleep apnoea

G6_SLEEPAPNO

sleep apnea: A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G47.3
  • Hospital discharge: ICD-9 3472
  • Cause of death: ICD-10 G47.3
  • Cause of death: ICD-9 3472

2 out of 7 registries used, show all original rules.

45212

4. Check minimum number of events

None

45212

5. Include endpoints

None

45212

6. Filter based on genotype QC (FinnGen only)

43899

Control definitions (FinnGen only)

Control exclude G6_NARCOCATA, G6_SLEEPDISOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G47
Name in latin Apnoea intrasomnalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 299915 99073 199632
Only index persons 288611 96978 191633
Unadjusted period prevalence (%)
Whole population 4.66 2.84 5.58
Only index persons 6.06 3.57 7.32
Median age at first event (years)
Whole population 54.62 57.21 53.35
Only index persons 54.55 57.21 53.21

-FinnGen-

Key figures

All Female Male
Number of individuals 43899 17701 26198
Unadjusted period prevalence (%) 11.70 7.69 14.41
Median age at first event (years) 56.38 56.85 56.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_SLEEPAPNO – Sleep apnoea

GWS hits: 28

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