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Restless leg syndrome

Endpoint Browser PheWeb

G6_RLS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — G25.8
  • Hospital discharge: ICD-10 — G25.8
  • Cause of death: ICD-10 — G25.8

3 out of 7 registries used, show all original rules.

3318

4. Check minimum number of events

None

3318

5. Include endpoints

None

3318

6. Filter based on genotype QC (FinnGen only)

3198

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF10

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22541 14134 8331
Only index persons 21977 13876 8101
Unadjusted period prevalence (%)
Whole population 0.34 0.40 0.23
Only index persons 0.44 0.51 0.31
Median age at first event (years)
Whole population 64.52 65.47 63.04
Only index persons 64.47 65.40 62.88

-FinnGen-

Key figures

All Female Male
Number of individuals 3198 2087 1111
Unadjusted period prevalence (%) 0.80 0.91 0.61
Median age at first event (years) 63.09 62.41 64.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_RLS – Restless leg syndrome

GWS hits: 8

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