≡ Risteys
FR+FG R10

Documentation Changelog GitHub Contact & Feedback

Postpolio syndrome

DOID EFO Endpoint Browser PheWeb

G6_POSTPOLIO

postpoliomyelitis syndrome: Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis (see this term), 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G14
  • Hospital discharge: ICD-9 — 138
  • Hospital discharge: ICD-8 — 4499
  • Cause of death: ICD-10 — G14
  • Cause of death: ICD-9 — 138
  • Cause of death: ICD-8 — 4499

2 out of 7 registries used, show all original rules.

67

4. Check minimum number of events

None

67

5. Include endpoints

None

67

6. Filter based on genotype QC (FinnGen only)

63

Control definitions (FinnGen only)

Control exclude G6_NEUATR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 981 555 407
Only index persons 561 364 197
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 58.18 58.22 57.94
Only index persons 52.38 53.03 51.18

-FinnGen-

Key figures

All Female Male
Number of individuals 63 36 27
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 50.50 47.57 54.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Relationships between endpoints

↥

Index endpoint: G6_POSTPOLIO – Postpolio syndrome

GWS hits: -

loading spinner Loading Relationships table