Paraplegia, diplegia of upper limbs

G6_PARDIPLE

paraplegia: Complete paralysis of the lower half of the body including both legs, often caused by damage to the spinal cord. [database_cross_reference: NCIT:P378]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

677

4. Check minimum number of events

None

677

5. Include endpoints

None

677

6. Filter based on genotype QC (FinnGen only)

661

Control definitions (FinnGen only)

Control exclude G6_CPETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7688 3418 4167
Only index persons 6093 2826 3267
Unadjusted period prevalence (%)
Whole population 0.11 0.10 0.12
Only index persons 0.12 0.10 0.12
Median age at first event (years)
Whole population 56.92 57.26 56.41
Only index persons 54.02 54.33 53.75

-FinnGen-

Key figures

All Female Male
Number of individuals 661 295 366
Unadjusted period prevalence (%) 0.17 0.13 0.20
Median age at first event (years) 54.56 47.18 60.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_PARDIPLE – Paraplegia, diplegia of upper limbs

GWS hits: 2

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