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Other and unspecified mononeuropathies, also in other diseases

DOID EFO Endpoint Browser PheWeb

G6_MONOOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G58.8, G58.9, G59*
  • Hospital discharge: ICD-9 — 3559
  • Hospital discharge: ICD-8 — 35708
  • Cause of death: ICD-10 — G58.8, G58.9, G59*
  • Cause of death: ICD-9 — 3559
  • Cause of death: ICD-8 — 35708

2 out of 7 registries used, show all original rules.

954

4. Check minimum number of events

None

954

5. Include endpoints

None

954

6. Filter based on genotype QC (FinnGen only)

925

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8773 4453 4216
Only index persons 7200 3834 3366
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.12
Only index persons 0.14 0.14 0.13
Median age at first event (years)
Whole population 48.22 48.19 48.05
Only index persons 46.27 46.67 45.82

-FinnGen-

Key figures

All Female Male
Number of individuals 925 522 403
Unadjusted period prevalence (%) 0.22 0.23 0.22
Median age at first event (years) 47.57 44.77 51.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_MONOOTHUNS – Other and unspecified mononeuropathies, also in other diseases

GWS hits: 1

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