Other and unspecified mononeuropathies of lower limb

G6_MONOLOWOTHUNS

mononeuropathy: Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G57.8, G57.9
  • Hospital discharge: ICD-9 355[7-8]
  • Cause of death: ICD-10 G57.8, G57.9
  • Cause of death: ICD-9 355[7-8]

2 out of 7 registries used, show all original rules.

865

4. Check minimum number of events

None

865

5. Include endpoints

None

865

6. Filter based on genotype QC (FinnGen only)

842

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6122 3829 2260
Only index persons 5614 3606 2008
Unadjusted period prevalence (%)
Whole population 0.09 0.11 0.06
Only index persons 0.11 0.13 0.08
Median age at first event (years)
Whole population 51.76 52.07 51.23
Only index persons 50.93 51.59 49.75

-FinnGen-

Key figures

All Female Male
Number of individuals 842 589 253
Unadjusted period prevalence (%) 0.22 0.26 0.14
Median age at first event (years) 52.54 51.65 54.60

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_MONOLOWOTHUNS – Other and unspecified mononeuropathies of lower limb

GWS hits: -

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