acute chest syndrome: A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
18198 |
4. Check minimum number of eventsNone |
18198 |
5. Include endpoints |
18271 |
6. Filter based on genotype QC (FinnGen only) |
17484 |
Control definitions (FinnGen only)
Control exclude
G6_EPIPAROX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G40-G47
Name in latin
Alia syndromata cephalalgica
Similar endpoints
↥List of similar endpoints to Other headache syndromes based on the number of shared cases.
Broader endpoints:
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Narrower endpoints:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 154528 | 105035 | 48504 |
Only index persons | 148177 | 101758 | 46419 |
Unadjusted period prevalence (%) | |||
Whole population | 2.48 | 3.01 | 1.36 |
Only index persons | 3.12 | 3.74 | 1.77 |
Median age at first event (years) | |||
Whole population | 46.78 | 47.56 | 45.27 |
Only index persons | 46.33 | 47.06 | 44.72 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 17484 | 12859 | 4625 |
Unadjusted period prevalence (%) | 4.78 | 5.58 | 2.54 |
Median age at first event (years) | 48.62 | 47.19 | 52.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: G6_HEADACHE – Other headache syndromes
GWS hits: 3
Loading Relationships table