Other headache syndromes

G6_HEADACHE

acute chest syndrome: A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G44
  • Hospital discharge: ICD-8 34601
  • Cause of death: ICD-10 G44
  • Cause of death: ICD-8 34601

2 out of 7 registries used, show all original rules.

18198

4. Check minimum number of events

None

18198

5. Include endpoints

18271

6. Filter based on genotype QC (FinnGen only)

17484

Control definitions (FinnGen only)

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Alia syndromata cephalalgica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 154528 105035 48504
Only index persons 148177 101758 46419
Unadjusted period prevalence (%)
Whole population 2.48 3.01 1.36
Only index persons 3.12 3.74 1.77
Median age at first event (years)
Whole population 46.78 47.56 45.27
Only index persons 46.33 47.06 44.72

-FinnGen-

Key figures

All Female Male
Number of individuals 17484 12859 4625
Unadjusted period prevalence (%) 4.78 5.58 2.54
Median age at first event (years) 48.62 47.19 52.58

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_HEADACHE – Other headache syndromes

GWS hits: 3

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