Cauda equina syndrome

G6_CAUDA

Cauda equina syndrome: Cauda equina syndrome refers to a group of symptoms that occur when some of the nerves in the cauda equina (the bundle of nerves that spread out from the bottom of the spinal cord) become compressed and/or damaged. Signs and symptoms of this condition include pain, numbness, or tingling in the lower back and/or legs; ' foot drop '; problems with bowel and/or bladder control; and sexual dysfunction. Cauda equina syndrome may be caused by a herniated disk , tumor , infection, fracture, or spinal stenosis . Treatment usually targets the underlying cause of the condition and often includes surgery to remove the material that is pressing on the nerves. Physical therapy , occupational therapy , and/or other services may be required if symptoms persist following surgery.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G83.4
  • Hospital discharge: ICD-9 3534B
  • Cause of death: ICD-10 G83.4
  • Cause of death: ICD-9 3534B

2 out of 7 registries used, show all original rules.

345

4. Check minimum number of events

None

345

5. Include endpoints

None

345

6. Filter based on genotype QC (FinnGen only)

329

Control definitions (FinnGen only)

Control exclude G6_CPETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G83
Name in latin Syndroma caudae equinae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3048 1653 1377
Only index persons 2805 1572 1233
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.06 0.05
Median age at first event (years)
Whole population 54.69 54.54 54.67
Only index persons 53.39 53.76 52.91

-FinnGen-

Key figures

All Female Male
Number of individuals 329 208 121
Unadjusted period prevalence (%) 0.08 0.09 0.07
Median age at first event (years) 51.82 49.74 55.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_CAUDA – Cauda equina syndrome

GWS hits: -

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