Carpal tunnel syndrome

G6_CARPTU

carpal tunnel syndrome: Entrapment of the median nerve in the wrist that is characterized by numbness, tingling and painful movement.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G56.0
  • Hospital discharge: ICD-9 3540
  • Cause of death: ICD-10 G56.0
  • Cause of death: ICD-9 3540

2 out of 7 registries used, show all original rules.

25488

4. Check minimum number of events

None

25488

5. Include endpoints

None

25488

6. Filter based on genotype QC (FinnGen only)

24766

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G56
Name in latin Syndroma canalis carpi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 197586 131488 65397
Only index persons 188924 126663 62261
Unadjusted period prevalence (%)
Whole population 3.11 3.77 1.83
Only index persons 3.91 4.66 2.38
Median age at first event (years)
Whole population 54.12 54.15 54.07
Only index persons 53.75 53.79 53.69

-FinnGen-

Key figures

All Female Male
Number of individuals 24766 17065 7701
Unadjusted period prevalence (%) 6.42 7.41 4.24
Median age at first event (years) 53.62 52.58 55.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_CARPTU – Carpal tunnel syndrome

GWS hits: 40

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