Alcohol induced polyneuropathy

G6_ALCOPOLY

alcoholic neuropathy: A condition where damage to the peripheral nervous system (including the peripheral elements of the autonomic nervous system) is associated with chronic ingestion of alcoholic beverages. The disorder may be caused by a direct effect of alcohol, an associated nutritional deficiency, or a combination of factors. Clinical manifestations include variable degrees of weakness; ATROPHY; PARESTHESIAS; pain; loss of reflexes; sensory loss; diaphoresis; and postural hypotension. (From Arch Neurol 1995;52(1):45-51; Adams et al., Principles of Neurology, 6th ed, p1146)

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G62.1
  • Hospital discharge: ICD-9 3575A
  • Cause of death: ICD-10 G62.1
  • Cause of death: ICD-9 3575A

2 out of 7 registries used, show all original rules.

288

4. Check minimum number of events

None

288

5. Include endpoints

None

288

6. Filter based on genotype QC (FinnGen only)

278

Control definitions (FinnGen only)

Control exclude G6_POLYNEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G62
Name in latin Polyneuropathia alcoholica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4609 835 3665
Only index persons 3095 628 2467
Unadjusted period prevalence (%)
Whole population 0.09 0.02 0.10
Only index persons 0.08 0.02 0.09
Median age at first event (years)
Whole population 57.12 56.02 57.32
Only index persons 57.57 57.05 57.70

-FinnGen-

Key figures

All Female Male
Number of individuals 278 55 223
Unadjusted period prevalence (%) 0.10 0.02 0.12
Median age at first event (years) 58.13 55.76 58.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_ALCOPOLY – Alcohol induced polyneuropathy

GWS hits: -

loading spinner Loading Relationships table