Volume depletion

E4_VOLUME

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E86
  • Hospital discharge: ICD-9 2765
  • Hospital discharge: ICD-8 7880
  • Cause of death: ICD-10 E86
  • Cause of death: ICD-9 2765
  • Cause of death: ICD-8 7880

2 out of 7 registries used, show all original rules.

3012

4. Check minimum number of events

None

3012

5. Include endpoints

None

3012

6. Filter based on genotype QC (FinnGen only)

2913

Control definitions (FinnGen only)

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E70-E90
Name in latin Depletio voluminis liquoris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 44655 24590 19806
Only index persons 37185 20583 16602
Unadjusted period prevalence (%)
Whole population 0.63 0.70 0.55
Only index persons 0.70 0.76 0.63
Median age at first event (years)
Whole population 77.57 81.19 73.09
Only index persons 77.71 81.39 73.15

-FinnGen-

Key figures

All Female Male
Number of individuals 2913 1249 1664
Unadjusted period prevalence (%) 0.76 0.54 0.92
Median age at first event (years) 71.83 69.88 73.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_VOLUME – Volume depletion

GWS hits: -

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