≡ Risteys
FR+FG R10

Documentation Changelog GitHub Contact & Feedback

Vitamin D deficiency

DOID EFO Endpoint Browser PheWeb

E4_VIT_D_DEF

ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E55
  • Hospital discharge: ICD-9 — 268
  • Hospital discharge: ICD-8 — 265
  • Cause of death: ICD-10 — E55
  • Cause of death: ICD-9 — 268
  • Cause of death: ICD-8 — 265

2 out of 7 registries used, show all original rules.

518

4. Check minimum number of events

None

518

5. Include endpoints

None

518

6. Filter based on genotype QC (FinnGen only)

482

Control definitions (FinnGen only)

Control exclude E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E50-E64
Name in latin Deficientia vitamini D

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5671 3233 2399
Only index persons 5177 2942 2235
Unadjusted period prevalence (%)
Whole population 0.08 0.09 0.07
Only index persons 0.10 0.11 0.09
Median age at first event (years)
Whole population 44.36 48.89 38.37
Only index persons 43.19 47.31 37.76

-FinnGen-

Key figures

All Female Male
Number of individuals 482 314 168
Unadjusted period prevalence (%) 0.12 0.14 0.09
Median age at first event (years) 49.55 46.86 54.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Relationships between endpoints

↥

Index endpoint: E4_VIT_D_DEF – Vitamin D deficiency

GWS hits: 1

loading spinner Loading Relationships table