Disorder of lipoprotein metabolism, unspecified

E4_LIPOPROTNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E78.8, E78.8+M14.3, E78.9
  • Hospital discharge: ICD-9 272[7-9]
  • Hospital discharge: ICD-8 27288|2729
  • Cause of death: ICD-10 E78.8, E78.8+M14.3, E78.9
  • Cause of death: ICD-9 272[7-9]
  • Cause of death: ICD-8 27288|2729

2 out of 7 registries used, show all original rules.

4545

4. Check minimum number of events

None

4545

5. Include endpoints

None

4545

6. Filter based on genotype QC (FinnGen only)

4382

Control definitions (FinnGen only)

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 35890 16241 19519
Only index persons 34064 15569 18495
Unadjusted period prevalence (%)
Whole population 0.51 0.47 0.55
Only index persons 0.64 0.57 0.71
Median age at first event (years)
Whole population 67.40 70.76 64.61
Only index persons 67.34 70.61 64.60

-FinnGen-

Key figures

All Female Male
Number of individuals 4382 1779 2603
Unadjusted period prevalence (%) 1.16 0.77 1.43
Median age at first event (years) 64.98 65.23 64.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_LIPOPROTNAS – Disorder of lipoprotein metabolism, unspecified

GWS hits: 10

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