Drug-induced hypoglycaemia without coma

E4_HYPODRUG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E16.0#
  • Hospital discharge: ICD-9 2510A
  • Cause of death: ICD-10 E16.0#
  • Cause of death: ICD-9 2510A

2 out of 7 registries used, show all original rules.

486

4. Check minimum number of events

None

486

5. Include endpoints

None

486

6. Filter based on genotype QC (FinnGen only)

477

Control definitions (FinnGen only)

Control exclude E4_GLUCOPANCREAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E16
Name in latin Hypoglychaemia ex medicamento sine comate

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4342 1947 2352
Only index persons 3451 1539 1912
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.07
Only index persons 0.07 0.06 0.07
Median age at first event (years)
Whole population 67.85 72.85 63.76
Only index persons 67.13 71.38 63.71

-FinnGen-

Key figures

All Female Male
Number of individuals 477 195 282
Unadjusted period prevalence (%) 0.13 0.08 0.16
Median age at first event (years) 58.59 51.56 63.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_HYPODRUG – Drug-induced hypoglycaemia without coma

GWS hits: -

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