Hyperosmolality and hypernatraemia

E4_HYPEROSMHNAT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E87.0
  • Hospital discharge: ICD-9 2760
  • Cause of death: ICD-10 E87.0
  • Cause of death: ICD-9 2760

2 out of 7 registries used, show all original rules.

377

4. Check minimum number of events

None

377

5. Include endpoints

None

377

6. Filter based on genotype QC (FinnGen only)

364

Control definitions (FinnGen only)

Control exclude E4_METABOLIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E87
Name in latin Hyperosmolalitas

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6622 3751 2831
Only index persons 5696 3249 2447
Unadjusted period prevalence (%)
Whole population 0.09 0.11 0.08
Only index persons 0.11 0.12 0.09
Median age at first event (years)
Whole population 77.28 80.01 73.68
Only index persons 77.45 80.17 73.85

-FinnGen-

Key figures

All Female Male
Number of individuals 364 164 200
Unadjusted period prevalence (%) 0.09 0.07 0.11
Median age at first event (years) 69.28 68.88 69.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_HYPEROSMHNAT – Hyperosmolality and hypernatraemia

GWS hits: -

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