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Secondary polycythaemia

DOID EFO Endpoint Browser PheWeb

D3_SCNDPOLYCYTHAEMIA

polycythemia: Abnormally high mass or concentration of red blood cells in the blood, either due to an increase in erythropoiesis or a decrease in plasma volume.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D75.1
  • Hospital discharge: ICD-9 — 2890
  • Hospital discharge: ICD-8 — 28900
  • Cause of death: ICD-10 — D75.1
  • Cause of death: ICD-9 — 2890
  • Cause of death: ICD-8 — 28900

2 out of 7 registries used, show all original rules.

677

4. Check minimum number of events

None

677

5. Include endpoints

None

677

6. Filter based on genotype QC (FinnGen only)

657

Control definitions (FinnGen only)

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D75
Name in latin Polycythaemia secundaria

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5793 1925 3795
Only index persons 4662 1564 3098
Unadjusted period prevalence (%)
Whole population 0.09 0.06 0.11
Only index persons 0.10 0.06 0.12
Median age at first event (years)
Whole population 58.75 60.79 57.65
Only index persons 57.47 60.07 56.16

-FinnGen-

Key figures

All Female Male
Number of individuals 657 215 442
Unadjusted period prevalence (%) 0.19 0.09 0.24
Median age at first event (years) 58.31 56.98 58.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: D3_SCNDPOLYCYTHAEMIA – Secondary polycythaemia

GWS hits: 1

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