hypersplenism: Overactive functioning of the spleen, resulting in excessive destruction of blood cells.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
114 |
4. Check minimum number of eventsNone |
114 |
5. Include endpointsNone |
114 |
6. Filter based on genotype QC (FinnGen only) |
112 |
Control definitions (FinnGen only)
Control exclude
D3_BLOODOTHER
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D73
Name in latin
Hypersplenismus
Similar endpoints
↥List of similar endpoints to
Hypersplenism
based on the number of shared cases.
Broader endpoints:
- Diseases of spleen
- Other diseases of blood and blood-forming organs
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1082 | 469 | 602 |
| Only index persons | 882 | 381 | 501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 58.66 | 59.57 | 57.67 |
| Only index persons | 56.73 | 57.62 | 56.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 112 | 50 | 62 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 59.22 | 56.20 | 61.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: D3_HYPERSPLENISM – Hypersplenism
GWS hits: -
Loading Relationships table