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Agranulocytosis

DOID EFO Endpoint Browser PheWeb

D3_AGRANULOCYTOSIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D70
  • Hospital discharge: ICD-9 — 2880
  • Hospital discharge: ICD-8 — 2889
  • Cause of death: ICD-10 — D70
  • Cause of death: ICD-9 — 2880
  • Cause of death: ICD-8 — 2889

2 out of 7 registries used, show all original rules.

3584

4. Check minimum number of events

None

3584

5. Include endpoints

None

3584

6. Filter based on genotype QC (FinnGen only)

3462

Control definitions (FinnGen only)

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D70-D77
Name in latin Agranulocytosis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26750 15948 10643
Only index persons 23160 14088 9072
Unadjusted period prevalence (%)
Whole population 0.39 0.46 0.30
Only index persons 0.45 0.52 0.35
Median age at first event (years)
Whole population 60.55 59.89 61.46
Only index persons 60.52 59.67 61.85

-FinnGen-

Key figures

All Female Male
Number of individuals 3462 2194 1268
Unadjusted period prevalence (%) 0.86 0.95 0.70
Median age at first event (years) 60.68 58.14 65.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: D3_AGRANULOCYTOSIS – Agranulocytosis

GWS hits: -

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