Acute posthaemorrhagic anaemia

D3_ACUTEPOSTBLEEDANAEMIA

Anemia, Hemolytic, Autoimmune: Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which various types of auto-antibodies are directed against red blood cells causing their survival to be shortened and resulting in hemolytic anemia.

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Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D62 Hospital discharge: ICD-9 — 2851A Cause of death: ICD-10 — D62 Cause of death: ICD-9 — 2851A 2 out of 7 registries used, show all original rules.	1100
4. Check minimum number of events None	1100
5. Include endpoints None	1100
6. Filter based on genotype QC (FinnGen only)	1057

Control definitions (FinnGen only)

Control exclude D3_APLASTICANDOTHANAEMIA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D60-D64

Name in latin Anaemia posthaemorrhagica acuta

NAME	D3_ACUTEPOSTBLEEDANAEMIA
CONTROL_EXCLUDE	D3_APLASTICANDOTHANAEMIA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D62
HD_ICD_9	2851A
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D62
COD_ICD_9	2851A
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Acute posthaemorrhagic anaemia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	15654	8391	7003
Only index persons	10414	5848	4566
Unadjusted period prevalence (%)
Whole population	0.22	0.24	0.20
Only index persons	0.20	0.21	0.17
Median age at first event (years)
Whole population	73.23	75.42	70.61
Only index persons	71.10	72.75	68.99

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	1057	479	578
Unadjusted period prevalence (%)	0.27	0.21	0.32
Median age at first event (years)	68.18	64.65	71.10

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Acute posthaemorrhagic anaemia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Acute posthaemorrhagic anaemia (D3_ACUTEPOSTBLEEDANAEMIA)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints