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Acquired pure red cell aplasia [erythroblastopenia]

DOID Endpoint Browser PheWeb

D3_ACQPUREREDCLLAPLASIA

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D60
  • Hospital discharge: ICD-9 — 2848C
  • Hospital discharge: ICD-8 — 28404
  • Cause of death: ICD-10 — D60
  • Cause of death: ICD-9 — 2848C
  • Cause of death: ICD-8 — 28404

2 out of 7 registries used, show all original rules.

138

4. Check minimum number of events

None

138

5. Include endpoints

None

138

6. Filter based on genotype QC (FinnGen only)

133

Control definitions (FinnGen only)

Control exclude D3_APLASTICANDOTHANAEMIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D60-D64
Name in latin Erythroblastopenia [pura] acquisita

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1585 812 763
Only index persons 1228 642 586
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 50.27 49.87 50.40
Only index persons 51.23 50.58 51.94

-FinnGen-

Key figures

All Female Male
Number of individuals 133 68 65
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 61.82 56.19 67.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: D3_ACQPUREREDCLLAPLASIA – Acquired pure red cell aplasia [erythroblastopenia]

GWS hits: -

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