Carcinoma in situ of skin (controls excluding all cancers)

CD2_INSITU_SKIN_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_SKIN
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D04
  • Cause of death: ICD-10 D04
  • Cancer registry: Topography ICD-O-3 C44
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9
Parent code in ICD-10 D00-D09
Name in latin Carcinoma in situ cervicis uteri

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23551 13334 10135
Only index persons 22087 12633 9454
Unadjusted period prevalence (%)
Whole population 0.34 0.38 0.28
Only index persons 0.42 0.46 0.36
Median age at first event (years)
Whole population 78.17 79.15 76.91
Only index persons 78.09 79.01 76.87

-FinnGen-

Key figures

All Female Male
Number of individuals 2135 1085 1050
Unadjusted period prevalence (%) 0.52 0.47 0.58
Median age at first event (years) 74.21 73.85 74.58

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CD2_INSITU_SKIN_EXALLC – Carcinoma in situ of skin (controls excluding all cancers)

GWS hits: 4

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